研究のタイプ: 医学/生物学の研究 (experimental study)

[ラットの出生前後の成長に対する子宮内でのWi-Fiばく露の影響] med./bio.

Effect of in utero wi-fi exposure on the pre- and postnatal development of rats

掲載誌: Birth Defects Res B Dev Reprod Toxicol 2012; 95 (2): 130-136

本研究では、妊娠した雌ラットを2450MHzのWi-Fi信号に全身SARを0.08、0.4、4W/kgの3つのばく露条件として、2時間/日、6日/週、18日間ばく露し、仔ラットにおける催奇形性及び発達への影響を評価した。その結果、全てのばく露条件について、妊娠ラット異常は認められず、最も高い4W/kgでも、出生前及び出生後の仔の発達に毒性有意な兆候は認められなかった。著者らは、本研究の結果は、現行のばく露限度値以下の携帯電話に関連したRF電磁界へのばく露による有害な影響は何ら検出されていないという、従来の結論を強めるものであるとしている。

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研究目的(著者による)

To study the effects of in utero exposure to a 2450 MHz WiFi signal on pregnant rats and their pups.

詳細情報

Dams were divided into five groups (20 animals/group): cage control, sham exposure group and three different exposure groups (with SAR levels of 0.08, 0.4 and 4 W/kg). Five dams per group were sacrificed and five female fetuses were investigated on day 20 of pregnancy (one day before expected delivery). Additionally, 15 dams per group and their offspring were observed for 28 days after delivery.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 2,450 MHz
ばく露時間: 2 h/day, 6 days/week for 18 days
  • SAR: 0.08 W/kg average over mass (whole body) (corresponds to public limit for RF exposure)
  • SAR: 0.4 W/kg average over mass (whole body) (corresponds to occupational limit for RF exposure)
  • SAR: 4 W/kg average over mass (whole body) (corresponds to critical level)

General information

Female rats were randomly distributed into five groups with 20 animals per group.

ばく露1

主たる特性
周波数 2,450 MHz
タイプ
  • electromagnetic field
ばく露時間 2 h/day, 6 days/week for 18 days
ばく露装置
チャンバの詳細 cubic reverberation chamber (150 x 150 x 150 cm)
ばく露装置の詳細 six antennas (70 W) provided uniform exposure; cages were placed in a 40 x 40 x 40 cm³ volume at the center of the chamber
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
SAR 0.08 W/kg average over mass - whole body corresponds to public limit for RF exposure
SAR 0.4 W/kg average over mass - whole body corresponds to occupational limit for RF exposure
SAR 4 W/kg average over mass - whole body corresponds to critical level

Reference articles

  • Wu T et al. (2010): [2.4GHzで動作する反響チャンバでの新生仔および若年のラットの全身ばく露評価]

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

For all experimental conditions, no abnormalities were noted in the pregnant rats and no significant signs of toxicity were observed in the prenatal and postnatal development of the pups, even at the highest level of 4 W/kg. In conclusion, no teratogenic effect of repeated exposures to the WiFi wireless communication signal was found.

研究の種別:

研究助成

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