Studientyp:
Medizinische/biologische Studie
(experimentelle Studie)
An evaluation of genotoxicity in human neuronal-type cells subjected to oxidative stress under an extremely low frequency pulsed magnetic field
med./bio.
[Eine Bewertung der Genotoxizität bei menschlichen neuronenartigen Zellen, die oxidativem Stress bei einem extrem niederfrequenten gepulsten Magnetfeld ausgesetzt sind]
Von:
Giorgi G, Lecciso M, Capri M, Lukas Yani S, Virelli A, Bersani F, Del Re B
Veröffentlicht in: Mutat Res Genet Toxicol Environ Mutagen 2014; 775: 31-37
a bipolar pulsed-square wave 50 Hz magnetic field was chosen with a duty cycle of 50%; rise time of the square, from peak to peak, was about 0.6 ms, resulting in an average rate of change of magnetic flux density of 3.3 T/s
two sets of horizontal Helmholtz coils, each of 25 cm diameter, with 40 (20 + 20) turns that were double-wrapped in order to obtain wound (active coil) or counter-wound configuration (sham exposure); active and sham coils were maintained in the same 5% CO2 incubator with a constant temperature of 37°C; samples were placed within a virtual cylinder (about 11 cm in height, and 4 cm in diameter), centered with respect to the coil system
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Effects of Single and Repeated Exposure to a 50-Hz 2-mT Electromagnetic Field on Primary Cultured Hippocampal Neurons
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Power Frequency Magnetic Fields Affect the p38 MAPK-Mediated Regulation of NB69 Cell Proliferation Implication of Free Radicals
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Extremely low frequency magnetic field (ELF-MF) exposure sensitizes SH-SY5Y cells to the pro-Parkinson's disease toxin MPP+
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Genomic instability induced by 50Hz magnetic fields is a dynamically evolving process not blocked by antioxidant treatment
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(2014):
Induction of genomic instability, oxidative processes, and mitochondrial activity by 50Hz magnetic fields in human SH-SY5Y neuroblastoma cells
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The Proliferative Response of NB69 Human Neuroblastoma Cells to a 50 Hz Magnetic Field is mediated by ERK1/2 Signaling
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Time-varying magnetic fields of 60 Hz at 7 mT induce DNA double-strand breaks and activate DNA damage checkpoints without apoptosis
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(2011):
Pre-Exposure to 50 Hz Magnetic Fields Modifies Menadione-Induced Genotoxic Effects in Human SH-SY5Y Neuroblastoma Cells
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Effect of ELF-EMF on number of apoptotic cells; correlation with reactive oxygen species and HSP
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Synergic effect of retinoic acid and extremely low frequency magnetic field exposure on human neuroblastoma cell line BE(2)C
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50-Hz extremely low frequency electromagnetic fields enhance cell proliferation and DNA damage: possible involvement of a redox mechanism
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Extremely low frequency magnetic fields and the promotion of H2O2-induced cell death in HL-60 cells
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Effects of 50 Hz electromagnetic field exposure on apoptosis and differentiation in a neuroblastoma cell line
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Decreased DNA repair rates and protection from heat induced apoptosis mediated by electromagnetic field exposure
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