Familial, environmental, and occupational risk factors in development of amyotrophic lateral sclerosis. epidem.

[Familiäre, umweltbedingte und berufliche Risikofaktoren für die Entwicklung von amyotrophe Lateralsklerose].

Ziel der Studie (lt. Autor)

Weitere Details

Endpunkt/Art der Risikoabschätzung

• neurodegenerative Erkrankungen: amyotrophe Lateralsklerose

Exposition

• • 50/60 Hz
  • elektrisches Feld
  • magnetisches Feld
  • Berührungsstrom
  • auch andere Expositionen ohne EMF
• • Hochspannungsfreileitung
  • Stromunfall
• • berufliche Exposition
  • persönliches Umfeld

Abschätzung

• Fragebogen: Stromschlag, Tätigkeit in einer Magnetfeld-Umgebung

Population

• Gruppe:
  • Männer
  • Frauen
• Alter: 15–80 Jahre
• Beobachtungszeitraum: Januar 2008 - Januar 2011
• Studienort: Indien (Burdwan)

Fallgruppe

• Merkmale: eindeutig diagnostizierte Fälle von amyotropher Lateralsklerose
• Datenquelle: Medizin-College und Krankenhaus von Burdwan

Kontrollgruppe

• Begleitpersonen der Fälle, jedoch keine Familienmitglieder; Patienten der Neurologie-Abteilung ohne neurologische oder medizinische Erkrankungen
• Matching:
  • Geschlecht
  • Altersgruppe

Studiengröße

Schlussfolgerung (lt. Autor)

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• Gunnarsson LG et al. (2019): Occupational Exposures and Neurodegenerative Diseases-A Systematic Literature Review and Meta-Analyses.
• Peters S et al. (2019): Associations of Electric Shock and Extremely Low-Frequency Magnetic Field Exposure With the Risk of Amyotrophic Lateral Sclerosis.
• Gunnarsson LG et al. (2018): Amyotrophic Lateral Sclerosis and Occupational Exposures: A Systematic Literature Review and Meta-Analyses.
• Huss A et al. (2018): Occupational exposure to extremely low-frequency magnetic fields and the risk of ALS: A systematic review and meta-analysis.
• Koeman T et al. (2017): Occupational exposure and amyotrophic lateral sclerosis in a prospective cohort.
• Vinceti M et al. (2017): Magnetic fields exposure from high-voltage power lines and risk of amyotrophic lateral sclerosis in two Italian populations.
• Fischer H et al. (2015): Occupational Exposure to Electric Shocks and Magnetic Fields and Amyotrophic Lateral Sclerosis in Sweden.
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