研究のタイプ: 医学/生物学の研究 (experimental study)

[ラットの空間的記憶に対する900MHz GSM電磁界への頭部のみの亜慢性および慢性のばく露の影響] med./bio.

Effect of head-only sub-chronic and chronic exposure to 900-MHz GSM electromagnetic fields on spatial memory in rats.

掲載誌: Brain Inj 2008; 22 (13-14): 1021-1029

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研究目的(著者による)

To study the effects of sub-chronic and chronic head exposure to 900 MHz on spatial memory of male rats.

詳細情報

30 rats each were exposed during 8 weeks (experiment 1: sub-chronic) and 24 weeks (experiment 2: chronic). Performance of exposed rats was compared with a sham exposure group, a negative control (no exposure) and a positive control (injection of scopolamine hydrobromide 0.1 mg/Kg before memory test). Effects of scopolamine involve impaired working memory in a radial-maze task.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: 45 min/day, 5 days/week for 8 weeks or 24 weeks
  • SAR: 1.5 W/kg average over mass (brain)
ばく露2: 900 MHz
Modulation type: pulsed
ばく露時間: 15 min/day, 5 days/week for 8 weeks or 24 weeks
  • SAR: 6 W/kg average over mass (brain)

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 45 min/day, 5 days/week for 8 weeks or 24 weeks
Modulation
Modulation type pulsed
Duty cycle 12.5 %
Repetition frequency 217 Hz
ばく露装置
ばく露の発生源/構造
  • loop antenna
ばく露装置の詳細 animals placed in 5 mm thick, 15 cm long plexiglas tubes with a diameter of 6 cm and a 3 cm long cone in which the rat's head was placed; antenna placed against the cone directly above the rat's head
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
SAR 1.5 W/kg average over mass - brain -

ばく露2

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 15 min/day, 5 days/week for 8 weeks or 24 weeks
Modulation
Modulation type pulsed
Duty cycle 12.5 %
Repetition frequency 217 Hz
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
SAR 6 W/kg average over mass - brain -

Reference articles

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

The results indicate that sub-chronic and chronic exposure of rats to GSM electromagnetic fields did not induce spatial memory deficit in the 8-arm radial maze. Scopolamine treatment in the positive control rats induced spatial memory deficits in the test.

研究の種別:

研究助成

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