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To study the effect of extremely low frequency magnetic fields most frequently used in magnetotherapy on reactive oxygen species generation in brain tissue of rats depending on the time of exposure.
30 animals were divided into one sham exposure group (n=10) and two exposure groups (each n=10; two different exposure durations: 30 min/day and 60 min/day).
ばく露時間: 30 min/day (group ii) respectively 60 min/day (group iii) for 10 days between 7 a.m. and 10 a.m.
30 rats were divided into three groups of 10 animals each: i) control group ii) and iii) experimental groups with different exposure duration
|ばく露時間||30 min/day (group ii) respectively 60 min/day (group iii) for 10 days between 7 a.m. and 10 a.m.|
|ばく露装置の詳細||rats in plastic containers were placed inside an applicator being part of the set for magnetotherapy|
|Sham exposure||A sham exposure was conducted.|
Extremely low frequency magnetic fields of 7 mT, 40 Hz, 30 min/day for 10 days caused a significant increase in lipid peroxidation and insignificant increases in hydrogen peroxide and free sulfhydryl groups as well as an insignificant decrease in the total protein content (as compared with the control group).
The same extremely low frequency magnetic fields but applied for 60 min/day caused insignificant increases in lipid peroxidation and hydrogen peroxide as well as significant increases in free sulfhydryl groups and protein concentration in the brain homogenates (as compared with the control group).
The effect of extremely low frequency magnetic field irradiation on oxidative stress parameters depended on the duration of magnetic field exposure.