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The effects of exposure of mice to a 60 Hz magnetic field on oxidative stress and the antioxidative defense in the brain should be investigated.
Mice were divided into two groups (n=14 each): an exposure group and a sham exposure group.
ばく露時間: continuous for 3 hours
|ばく露時間||continuous for 3 hours|
|チャンバの詳細||cage made of non-magnetic material|
|ばく露装置の詳細||Helmholtz coils (1 m2, 100 turns of 1 mm copper wire) were embedded in an open wooden rectangular frame; each winding was split allowing the current to flow in the same sense through each half of the winding (field aiding); coils produced a MF in the horizontal direction at the center of the system|
|Sham exposure||A sham exposure was conducted.|
|磁束密度||1.2 mT||effective value||測定値||-||-|
The amount of reactive oxygen species was not significantly different between the exposure and sham exposure group. However, lipid peroxidation and the superoxide dismutase enzyme activity were significantly increased in the exposure group compared to the sham exposure group.
The authors conclude that exposure of mice to a 60 Hz magnetic field could cause oxidative stress and deteriorate the antioxidative defense in the brain.