研究のタイプ: 医学/生物学の研究 (experimental study)

[900 MHzマイクロ波放射はラットの脳における酸化を促進する] med./bio.

900-MHz microwave radiation promotes oxidation in rat brain.

掲載誌: Electromagn Biol Med 2011; 30 (4): 219-234

この研究では、1日あたり2時間、45日間の900MHzの携帯電話のRF電磁界(SAR0.9W/kg)へのばく露がWistarラットの脳内の坑酸化酵素活性等に及ぼす影響を調べた。その結果、坑酸化酵素活性、プロテインキナーゼC、メラトニンカスパーゼ3、クレアチンキナーゼの低下または上昇、活性酸素種ROS)の過剰生成などのバイオマーカにおける有意な影響が認められ、これらは健康上の意味合いがある可能性を示唆すると結論している。

The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →

研究目的(著者による)

To study the effect of mobile exposure on different regions of the rat brain.

詳細情報

Six animals were exposed and six animals were sham exposed.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for 2 h/day on 45 days
  • 電力: 2 mW maximum
  • SAR: 0.9 W/kg average over time (manufacturer's data)

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 2 h/day on 45 days
Modulation
Modulation type pulsed
Repetition frequency 216.7 Hz
Additional information

burst width: 0.577 ms

ばく露装置
ばく露の発生源/構造
  • セルラ-電話
ばく露装置の詳細 rats placed individually in 18 - 22 cm long, 5.7 cm high and 4 - 7 cm wide Plexiglas cages, fixed with anechoic material and ventilated with 1 cm diameter holes; mobile phone positioned on top of the cage; mobility of the rats in the cage limited to 1 - 2 cm; cell phones in stand-by mode (missed call); each missed call lasted 1 min, separated by 15 s intervals
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
電力 2 mW maximum 測定値 - -
SAR 0.9 W/kg average over time - - manufacturer's data

Reference articles

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

The data showed a significant decrease in the enzyme activities of glutathione peroxidase and superoxide dismutase, and an increase in catalase enzyme activity. Protein kinase C enzyme activity was significantly decreased in the samples of the exposed group (hippocampus and whole brain). Also, a significant decrease in the level of pineal melatonin and a significant increase in creatine kinase and caspase 3 enzyme activities was observed in the exposed group (whole brain) compared with the sham exposed group. Finally, a significant increase in the level of reactive oxygen species was also recorded.
The authors conclude that a decrease or an increase in antioxidative enzyme activities, protein kinase C, melatonin, caspase 3, and creatine kinase enzyme activities are related to an overproduction of reactive oxygen species in the animals under mobile phone exposure.

研究の種別:

研究助成

関連論文