この研究は、オスのSprague-Dawleyラットの精巣機能に対する1.95 GHz電磁界（EMF）の影響を調べた。5週齢のラットを3群（各n = 24）に分け、擬似ばく露対照群および2つのEMFばく露群（全身平均SARが0.4 W / kgおよび0.08 W / kg）とした。1.95 GHzの広帯域符号分割多元接続（W-CDMA）信号への全身ばく露を、1日5時間、週7日で、5週間（生殖成熟期である5〜10週齢の期間）与えた。その結果、体重増加、精巣・精巣上体・精嚢・前立腺の重量に3群間での差はなかった；精巣および精巣上体中の精子の数はEMFばく露群では減少しないどころか、0.4 W / kgのSARばく露群では精巣の精子数は有意に増加した；精子の運動性または形態、および精子形成周期の段階の精子を含む精細管での組織学的外観において異常は観察されなかった；以上の知見から、この実験に用いたばく露条件下で精巣毒性の証拠はなかった、と報告している。
The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →
To study the effects of whole body exposure to 1.95 GHz on rat testes.
Five week old animals were divided into three groups of 24 each and exposed for five weeks (from the age of 5 to 10 weeks, corresponding to reproductive maturation in the rat).
|ばく露時間||continuous for 5 h/day, 7 days/week during 5 weeks|
|ばく露装置の詳細||90 cm x 90 cm x 40 cm exposure boxes with inside dimensions of 70 cm x 70 cm x 34 cm covered on the inside with 6 cm thick planar RF absorbers, except for the ceiling, which was made of metal mesh and covered with a 4.2 mm thick translucent acrylic plate; a turntable covered with a 2 mm thick reflector plate was placed inside the box, with which the EMF exposure to the front side including the testis was increased; four 200 mm x 190 mm acrylic cages, housing 1 rat each, cylindrically arranged in the exposure chamber; two antennas covered with a ABS resin cap, crossing at a right angle and with a spacing of 40 mm hanging from the ceiling in the center of the exposure box|
|Sham exposure||A sham exposure was conducted.|
There were no differences in body weight gain or weights of the testis, epididymis, seminal vesicles, and prostate among the groups. The number of sperms in the testis and epididymis were not decreased in the electromagnetic field exposed groups. The testicular sperm count was even significantly increased with the 0.4 W/kg SAR. Abnormalities of sperm motility or morphology and the histological appearance of seminiferous tubules, including the stage of the spermatogenic cycle, were not found.
In conclusion, under the present exposure conditions no testicular toxicity was evident.