The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →
To study the effects of cell phone exposure on the fatty acid composition in phospholipids, malondialdehyde concentration, p53 immune reactivity and histological structure of the rat brain.
It is suggested that p53 immune reactivity may be related to the change of fatty acid composition in phospholipids. The loss of p53 appears to sensitize cells to fatty acid synthase inhibitors, and raises the possibility that these agents may be clinically useful against malignancies.
Malondialdehyde is a marker for lipid peroxidation, free radical damage, and oxidative stress. Lipid peroxidation may induce p53 immune reactivity.
|ばく露時間||repeated daily exposure, 20 min/day for 1 month|
|Repetition frequency||217 Hz|
DTX (discontinuous transmission mode) was activated. The phones were in speech condition sending a tape of human speech to the base station.
|Distance between exposed object and exposure source||0.5 cm|
|チャンバの詳細||The rats were confined in Plexiglas cages (20 cm x 10.5 cm x 10 cm) with ventilation holes, and the cellular phones were placed 0.5 cm under the cages.|
|ばく露装置の詳細||Exposure began after the rats had selected a fixed location and settled into a prone position. The feed point of the antenna was placed under the cage against the brain.|
|Additional information||For sham exposure, the setup was identical, except that the phone was switched off.|
Histological alteration and changes in brain phospholipid fatty acids composition were not found in the brains. p53 immune reactivity was not affected by cell phone exposure. Malondialdehyde concentration in exposed brains was significantly higher than in sham-exposed brains. The alteration in malondialdehyde does not appear sufficient to induce histological changes in brain tissue.