研究のタイプ: 医学/生物学の研究 (experimental study)

[900 MHzGSM携帯電話はラットの脳に影響するか] med./bio.

Does 900 MHz GSM Mobile Phone Exposure Affect Rat Brain?

掲載誌: Electromagn Biol Med 2004; 23 (3): 201-214

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研究目的(著者による)

To study the effects of cell phone exposure on the fatty acid composition in phospholipids, malondialdehyde concentration, p53 immune reactivity and histological structure of the rat brain.

詳細情報

It is suggested that p53 immune reactivity may be related to the change of fatty acid composition in phospholipids. The loss of p53 appears to sensitize cells to fatty acid synthase inhibitors, and raises the possibility that these agents may be clinically useful against malignancies.
Malondialdehyde is a marker for lipid peroxidation, free radical damage, and oxidative stress. Lipid peroxidation may induce p53 immune reactivity.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 890–915 MHz
Modulation type: pulsed
ばく露時間: repeated daily exposure, 20 min/day for 1 month

ばく露1

主たる特性
周波数 890–915 MHz
タイプ
  • electromagnetic field
ばく露時間 repeated daily exposure, 20 min/day for 1 month
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
Additional information

DTX (discontinuous transmission mode) was activated. The phones were in speech condition sending a tape of human speech to the base station.

ばく露装置
ばく露の発生源/構造
  • セルラ-電話
Distance between exposed object and exposure source 0.5 cm
チャンバの詳細 The rats were confined in Plexiglas cages (20 cm x 10.5 cm x 10 cm) with ventilation holes, and the cellular phones were placed 0.5 cm under the cages.
ばく露装置の詳細 Exposure began after the rats had selected a fixed location and settled into a prone position. The feed point of the antenna was placed under the cage against the brain.
Additional information For sham exposure, the setup was identical, except that the phone was switched off.
パラメータ
測定量 種別 Method Mass 備考
電力 2 W peak - - -
電力 250 mW mean - - -
電界強度 13.59 V/m mean 測定値 - -
電力密度 0.047 mW/cm² mean 測定値 - -
SAR 3.13 W/kg effective value 計算値 1 g -
SAR 0.52 W/kg effective value 測定値および計算値 whole body 0.29-0.87 W/kg

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

Histological alteration and changes in brain phospholipid fatty acids composition were not found in the brains. p53 immune reactivity was not affected by cell phone exposure. Malondialdehyde concentration in exposed brains was significantly higher than in sham-exposed brains. The alteration in malondialdehyde does not appear sufficient to induce histological changes in brain tissue.

研究の種別:

研究助成

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