研究のタイプ: 医学/生物学の研究 (experimental study)

[イチョウの葉はラットの脳における携帯電話による酸化ストレスを防止する] med./bio.

Ginkgo biloba prevents mobile phone-induced oxidative stress in rat brain.

掲載誌: Clin Chim Acta 2004; 340 (1-2): 153-162

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研究目的(著者による)

To investigate the effect of Ginkgo biloba extracts on mobile phone induced oxidative stress in brain tissue of rats.

詳細情報

Ginkgo extracts were feed to rats as dry powder. Specific metabolites such as malondialdehyde and nitric oxide (NO) and a broad variety of enzymes involved in antioxidative metabolism were investigated.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: CW
ばく露時間: repeated daily exposure, 1 h/day for 7 days
  • SAR: 2 W/kg maximum (peak SAR of the brain)
  • SAR: 0.25 W/kg average over mass (whole body)

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
特性
  • near field
ばく露時間 repeated daily exposure, 1 h/day for 7 days
Modulation
Modulation type CW
ばく露装置
ばく露の発生源/構造
チャンバの詳細 The exposure system was based on the reference article with some modifications. It consisted of six round ventilated tubes mounted circularly and two (?) mobile phones in the middle on top of them.
ばく露装置の詳細 Rats were confined in the tubes with their heads directed towards the antennas of the mobile phones. Mobile phones were activated by calling each other.
Additional information Rats were divided into four exposure groups: EMR, EMR + Gb (Gingko biloba), Gb only, and controls. Control and Gb only groups were subjected to the same conditions except that the mobile phones were turned off.
パラメータ
測定量 種別 Method Mass 備考
SAR 2 W/kg maximum - - peak SAR of the brain
SAR 0.25 W/kg average over mass - whole body -

Reference articles

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

The three main outcomes of this study on rat brain can be resumed as followed:
1) mobile phones can induce oxidative damage. This is shown by increased levels of malondialdehyde, nitric oxide, xanthine oxidase, and adenosine deaminase.
2) Alterations in brain are histopathologically detectable.
3) Ginkgo biloba extracts act as a free radical scavenger agent and prevents oxidative damage and histopathological changes.

研究の種別:

研究助成

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