Authors | Year | Exposed system | Endpoints | Frequency range | SAR | Exposure duration | Parameters |
---|---|---|---|---|---|---|---|
Hirose H et al. | 2007 | 無傷細胞/細胞培養, A172 (human glioblastoma cells) and IMR90 fibroblasts (from fetal lungs) | cellular stress response (Hsp27 (heat-shock protein 27) content and hsp27 phosphorylation) | 2.1425 GHz | 80–800 mW/kg | continuous for 2, 24, or 48 h for A172 cells | 携帯電話基地局, CDMA, 移動体通信システム, マイクロ波 |
Goswami PC et al. | 1999 | 無傷細胞/細胞培養, C3H 10T1/2 cells (derived from mouse embryo fibroblasts) | stress response (proto-oncogene expression and DNA-binding activity of transcription factors) | 835.62 MHz | 0.6 W/kg | continuous for 24 h or 4 days | 移動体通信システム, CDMA |
Leszczynski D et al. | 2002 | 無傷細胞/細胞培養, EA.hy926 cells | activation of signal transduction pathways and induction of cellular stress response (expression status of heat shock protein 27 and p38MAPK) | 900 MHz | 2 W/kg | continuous for 1 h | GSM, 移動体通信システム, マイクロ波 |
Liu C et al. | 2013 | 無傷細胞/細胞培養, GC-2 cells (murine spermatocyte-derived cell line) | DNA damage, oxidative stress | 1,800 MHz | 1–4 W/kg | intermittent (5 min on, 10 min off) for 24 hours | 携帯電話, GSM, 移動体通信システム |
Liu K et al. | 2014 | 無傷細胞/細胞培養, GC-2 cells (murine spermatocyte-derived cell line) | - | 1,800 MHz | 1–4 W/kg | intermittent for 24 hours (5 min on and 10 min off) | 携帯電話, GSM, 移動体通信システム |
Huang TQ et al. | 2008 | 無傷細胞/細胞培養, HEI-OC1 cells (immortalized mouse auditory hair cells) | cell cycle, DNA damage, stress response, and gene expression | 1,763 MHz | 20 W/kg | continuous for 24 h and 48 h | 移動体通信システム, 携帯電話, CDMA |
Sefidbakht Y et al. | 2014 | 無傷細胞/細胞培養, HEK 293T cells (human embryonic kidney cells) transfected with luciferase gene | luciferase enzyme activity and oxidative stress | 940 MHz | 0.09 W/kg | continuous for up to 90 minutes | 携帯電話, 移動体通信システム |
Lee JS et al. | 2016 | 無傷細胞/細胞培養, HT22 (mouse hippocampus neuronal cells) | cytotoxicity | 837–1,950 MHz | 2 W/kg | continuous for 2 hours | 携帯電話, CDMA, W-CDMA, 移動体通信システム, 非EMF, 共ばく露 |
Laszlo A et al. | 2005 | 無傷細胞/細胞培養, HeLa S3 (human cervical carcinoma cell line); hamster ovary HA-1 fibroblasts; C3H 10T1/2 (mouse fibroblast cells) | stress response (DNA-binding activity of heat-shock factor) | 835.62 MHz | 0.6–5 W/kg | continuous for 5, 15, 30 and 60 min or 24 h | CDMA, FDMA, 移動体通信システム, マイクロ波 |
Hook GJ et al. | 2004 | 無傷細胞/細胞培養, J774.16 (mouse macrophage cells) | oxidative stress | 835.62 MHz | 800 µW/g | continuous for 20 to 22 h | CDMA, 移動体通信システム, CW 連続波 |
Lee JS et al. | 2006 | 無傷細胞/細胞培養, Jurkat cells (T lymphocyte hybridoma cell line) and rat primary astrocytes | cellular stress response | 1,762.5 MHz | 2–20 W/kg | continuous for 30 min or 1 h | デジタル携帯電話, CDMA, 移動体通信システム |
Brescia F et al. | 2009 | 無傷細胞/細胞培養, Jurkat cells (human lymphoblastoid T cells) | oxidative stress (production of reactive oxygen species), cell viability | 1,950 MHz | 0.5–2 W/kg | 5 min - 60 min or 24 h | デジタル携帯電話, UMTS, 移動体通信システム, 共ばく露 |
Cig B et al. | 2015 | 無傷細胞/細胞培養, MCF-7 (human breast cancer cell line) | apoptosis, cytosolic Ca<sup>2+</sup> concentration, generation of reactive oxygen species | 900 MHz | 0.18–0.58 mW/kg | continuous for 1 hour | 携帯電話, GSM, 移動体通信システム, W-LAN/WiFi, 2.45 GHz |
Stander BA et al. | 2011 | 無傷細胞/細胞培養, MCF-7 (human breast cancer cell line) | - | 900 MHz | - | - | 移動体通信システム, 携帯電話, GSM, RF電磁界 |
Hong MN et al. | 2012 | 無傷細胞/細胞培養, MCF10 A cells (human breast epithelial cells) | oxidative stress | 837 MHz | 2–4 W/kg | continuous for 2 h | 携帯電話, CDMA, W-CDMA, 移動体通信システム |
Kahya MC et al. | 2014 | 無傷細胞/細胞培養, MDA-MB-231 cells (breast cancer cell line) | - | 900 MHz | 0.36 W/kg | - | 携帯電話, GSM, 移動体通信システム, 共ばく露 |
Miyakoshi J et al. | 2005 | 無傷細胞/細胞培養, MO54 cells (derived from a human malignant glioma) | activation of stress response genes | 1,950 MHz | 1–10 W/kg | continuous for 1 or 2 h | 移動体通信システム |
Lantow M et al. | 2006 | 無傷細胞/細胞培養, Mono Mac 6 (human monocytes) and K562 cells (human erythroleukemic cell line) | stress response (production of free radicals and expression of heat shock proteins) | 1,800 MHz | 0.5–2 W/kg | continuous for 45 min | GSM, 移動体通信システム |
Simko M et al. | 2006 | 無傷細胞/細胞培養, Mono Mac 6 cells (human monocytes) | stress protein expression and free radical release | 1,800 MHz | 2 W/kg | continuous for 60 min | GSM, 移動体通信システム |
Hou Q et al. | 2015 | 無傷細胞/細胞培養, NIH3T3 cells (mouse fibroblast cell line) | oxidative stress, DNA damage and apoptosis in mouse embryonic fibroblasts | 1,800 MHz | 2 W/kg | intermittent exposure (5 min on/10 min off) for 0.5, 1, 1.5, 2, 4, 6 or 8 hours | 携帯電話, GSM, 移動体通信システム |
Kang KA et al. | 2014 | 無傷細胞/細胞培養, NIH3T3 cells (mouse fibroblasts), U87 (human glioma cells), PC12 (rat pheochromocytoma cells), SH-SY5Y (human neuroblastoma cells) | cell viability, oxidative stress | 837–1,950 MHz | 2 W/kg | continuous for 2 hours | 携帯電話, CDMA, W-CDMA, 移動体通信システム, 共ばく露 |
Wang X et al. | 2015 | 無傷細胞/細胞培養, Neuro-2a (mouse neuroblastoma) cells | DNA damage, oxidative stress and cell viability | 900 MHz | 0.5–2 W/kg | continuous for 24 hours | 携帯電話, GSM, 移動体通信システム, 共ばく露 |
Luukkonen J et al. | 2009 | 無傷細胞/細胞培養, SH-SY5Y (human neuroblastoma cell line) | DNA damage, production of reactive oxygen species | 872 MHz | 5 W/kg | continuous for 1 h | GSM, 移動体通信システム, RF電磁界, CW 連続波, 共ばく露 |
Luukkonen J et al. | 2010 | 無傷細胞/細胞培養, SH-SY5Y (human neuroblastoma cell line) | DNA damage, reactive oxygen species production | 872 MHz | 5 W/kg | continuous for 1 h for the ROS production experiment; continuous for 3 hr for the comet assay experiment | 携帯電話, GSM, 移動体通信システム, RF電磁界, CW 連続波, PW パルス波 |
Calabro E et al. | 2012 | 無傷細胞/細胞培養, SH-SY5Y (human neuroblastoma cell line) | cellular stress response (heat shock protein expression, cell viability and apoptosis) | 1,760 MHz | 0.086 W/kg | continuous for 2 h and 4 h | 携帯電話, GSM, 移動体通信システム |
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