Studientyp:
Medizinische/biologische Studie
(experimentelle Studie)
Synergism between sinusoidal-50 Hz magnetic field and formaldehyde in triggering carcinogenic effects in male Sprague-Dawley rats
med./bio.
[Synergismus zwischen einem sinusförmigen 50 Hz-Magnetfeld und Formaldehyd beim Hervorrufen von karzinogenen Wirkungen in männlichen Sprague-Dawley-Ratten]
Von:
Soffritti M, Tibaldi E, Padovani M, Hoel DG, Giuliani L, Bua L, Lauriola M, Falcioni L, Manservigi M, Manservisi F, Belpoggi F
Veröffentlicht in: Am J Ind Med 2016; 59 (7): 509-521
rats in cages were placed in a large room with a temperature of 22°C ± 3°C and a relative humidity of 40-60%
Aufbau
the field lines were horizontal and parallel to the ground; the field uniformity was better than 10%; there was no noise or vibration from current generator and coils; a maximum variation of 2°C was tolerated near coils; the 24 coils had a toroidal shape and were made of three turns of an insulated copper cable, mounted on a superstructure of aluminum composed of two insulated parts in order to avoid a closed loop subject to total field; the total copper cross-section was 11 mm x 28 mm; mounted inside the toroidal magnet was a wooden support structure for rat cages; each toroidal device was designed for the allocation of 500 rats, 5 per cage, distributed on five levels; the toroidal device had an external diameter of 4.7 m and was 2.1 m high
Zusatzinfo
control animals stayed in the same room as the exposed animals
Istituto Nazionale Per L'Assicurazione Contro Gli Infortuni Sul Lavoro (INAIL; Italian Workers' Compensation Authority), Italy
Istituto Ramazzini, Italy
Regional Agency for the Prevention and the Environment of the Emilia-Romagna Region (Agenzia Regionale per la Prevenzione e l'Ambiente dell'Emilia-Romagna, ARPA), Italy
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