Studientyp:
Medizinische/biologische Studie
(experimentelle Studie)
The effect of extremely low frequency electromagnetic fields (ELF-EMF) on the frequency of micronuclei and sister chromatid exchange in human lymphocytes induced by benzo(a)pyrene.
med./bio.
[Die Wirkung extrem niederfrequenter elektromagnetischer Felder (ELF-EMF) auf die Häufigkeit von Mikronuklei und Schwesterchromatid-Austausch bei menschlichen Lymphozyten, welche durch Benzo(a)pyren induziert wurden].
Von:
Cho YH, Chung HW
Veröffentlicht in: Toxicol Lett 2003; 143 (1): 37-44
Walleczek J, Shiu E.C, Hahn G.M, 1999 Increase in radiation induced HPRTgenemutation frequency after non thermal exposure to non ionizing 60 Hz electromagnetic fields. Radiat. Res. 151, 489-497.
Expositionsaufbau
Expositionsquelle
two solenoids coils, 0.3 m in length and 0.15 m in diameter with 350 turns/m
Aufbau
Culture plates placed in the center of the exposure system where the magnetic field was 2.5% homogeneous. The sham exposed cultures were tested with the same exposure system with the power supply switched off.
Villarini M et al.
(2017):
No evidence of DNA damage by co-exposure to extremely low frequency magnetic fields and aluminum on neuroblastoma cell lines.
Kesari KK et al.
(2016):
Induction of micronuclei and superoxide production in neuroblastoma and glioma cell lines exposed to weak 50 Hz magnetic fields.
Li Y et al.
(2014):
Extra-low-frequency magnetic fields alter cancer cells through metabolic restriction.
Jin YB et al.
(2014):
Absence of DNA damage after 60-Hz electromagnetic field exposure combined with ionizing radiation, hydrogen peroxide, or c-Myc overexpression.
Luukkonen J et al.
(2014):
Induction of genomic instability, oxidative processes, and mitochondrial activity by 50Hz magnetic fields in human SH-SY5Y neuroblastoma cells.
Jin YB et al.
(2012):
Effects on micronuclei formation of 60-Hz electromagnetic field exposure with ionizing radiation, hydrogen peroxide, or c-Myc overexpression.
Miyakoshi Y et al.
(2012):
Tempol suppresses micronuclei formation in astrocytes of newborn rats exposed to 50-Hz, 10-mT electromagnetic fields under bleomycin administration.
Luukkonen J et al.
(2011):
Pre-Exposure to 50 Hz Magnetic Fields Modifies Menadione-Induced Genotoxic Effects in Human SH-SY5Y Neuroblastoma Cells.
Markkanen A et al.
(2008):
Pre-exposure to 50 Hz magnetic fields modifies menadione-induced DNA damage response in murine L929 cells.
Mairs RJ et al.
(2007):
Microsatellite analysis for determination of the mutagenicity of extremely low-frequency electromagnetic fields and ionising radiation in vitro.
Wahab MA et al.
(2007):
Elevated sister chromatid exchange frequencies in dividing human peripheral blood lymphocytes exposed to 50 Hz magnetic fields.
Cho YH et al.
(2007):
Effects of extremely low-frequency electromagnetic fields on delayed chromosomal instability induced by bleomycin in normal human fibroblast cells.
Hone P et al.
(2006):
Chromatid damage in human lymphocytes is not affected by 50 Hz electromagnetic fields.
Winker R et al.
(2005):
Chromosomal damage in human diploid fibroblasts by intermittent exposure to extremely low-frequency electromagnetic fields.
Testa A et al.
(2004):
Evaluation of genotoxic effect of low level 50 Hz magnetic fields on human blood cells using different cytogenetic assays.
Stronati L et al.
(2004):
Absence of genotoxicity in human blood cells exposed to 50 Hz magnetic fields as assessed by comet assay, chromosome aberration, micronucleus, and sister chromatid exchange analyses.
Koyama S et al.
(2004):
ELF electromagnetic fields increase hydrogen peroxide (H2O2)-induced mutations in pTN89 plasmids.
Pasquini R et al.
(2003):
Micronucleus induction in cells co-exposed in vitro to 50 Hz magnetic field and benzene, 1,4-benzenediol (hydroquinone) or 1,2,4-benzenetriol.
Verheyen GR et al.
(2003):
Effect of coexposure to 50 Hz magnetic fields and an aneugen on human lymphocytes, determined by the cytokinesis block micronucleus assay.
Ding GR et al.
(2003):
Induction of kinetochore-positive and kinetochore-negative micronuclei in CHO cells by ELF magnetic fields and/or X-rays.
Simko M et al.
(2001):
Micronucleus induction in Syrian hamster embryo cells following exposure to 50 Hz magnetic fields, benzo(a)pyrene, and TPA in vitro.
Zeni O et al.
(2001):
Combined exposure to extremely low frequency (ELF) magnetic fields and chemical mutagens: Lack of genotoxic effects in human lymphocytes
Maes A et al.
(2000):
Cytogenetic effects of 50 Hz magnetic fields of different magnetic flux densities.
Scarfi MR et al.
(1999):
Micronucleus frequency and cell proliferation in human lymphocytes exposed to 50 Hz sinusoidal magnetic fields.
Yaguchi H et al.
(1999):
Effect of high-density extremely low frequency magnetic field on sister chromatid exchanges in mouse m5S cells.
Simko M et al.
(1998):
Effects of 50 Hz EMF exposure on micronucleus formation and apoptosis in transformed and nontransformed human cell lines.
Lagroye I et al.
(1997):
The effect of 50 Hz electromagnetic fields on the formation of micronuclei in rodent cell lines exposed to gamma radiation.
Scarfi MR et al.
(1997):
50-Hz, 1-mT sinusoidal magnetic fields do not affect micronucleus frequency and cell proliferation in human lymphocytes from normal and Turner's syndrome subjects.
Scarfi MR et al.
(1993):
50 Hz AC sinusoidal electric fields do not exert genotoxic effects (micronucleus formation) in human lymphocytes.
Scarfi MR et al.
(1991):
Spontaneous and mitomycin-C-induced micronuclei in human lymphocytes exposed to extremely low frequency pulsed magnetic fields.
Khalil AM et al.
(1991):
Cytogenetic effects of pulsing electromagnetic field on human lymphocytes in vitro: chromosome aberrations, sister-chromatid exchanges and cell kinetics.
Cohen MM et al.
(1986):
The effect of low-level 60-Hz electromagnetic fields on human lymphoid cells. II. Sister-chromatid exchanges in peripheral lymphocytes and lymphoblastoid cell lines.
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