Es sollten die kurzfristigen (7 Tage) und langfristigen (25 Tage) Wirkungen extrem niederfrequenterMagnetfelder auf das räumliche Erkennungs-Gedächtnis bei Mäusen (n=23) untersucht werden.
Hintergrund/weitere Details
Es wurde ein Y-Labyrinth genutzt, das auf der angeborenen Neigung von Nagetieren aufbaut, neue Umwelten zu entdecken: Während des ersten Versuchsdurchlaufs wurde der Maus erlaubt, lediglich zwei Arme des Labyrinths zu erforschen (der Dritte wurde durch eine Tür verschlossen). Während des zweiten Versuchsdurchlaufs wurde die Tür geöffnet und alle drei Arme waren zugänglich. Die Unterscheidung zwischen dem Reiz des Neuen und dem Vertrauten kann untersucht werden, indem die Erforschung aller drei Arme durch das Tier miteinander verglichen werden.
coil consisting of four layers of 250 turns each wrapped horizontally around a 70 cm x 40 cm x 43 cm plastic frame; mice placed in a plastic box on a wooden table in the center of the coil
Chinese-Finnish International Collaboration Project NEURO
Major State Basic Research Development Program, China
National Basic Research Program (Program 973), China
National High-tech R&D Program (863 Program), China
National Key Technologies R&D Program, China
Program of CASC
Yunnan Science and Technique Program, China
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Effects of exposure to extremely low-frequency electromagnetic fields on spatial and passive avoidance learning and memory, anxiety-like behavior and oxidative stress in male rats
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Effects of extremely low frequency electromagnetic fields (100 µT) on behaviors in rats
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(2015):
Neuritin reverses deficits in murine novel object associative recognition memory caused by exposure to extremely low-frequency (50 Hz) electromagnetic fields
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(2014):
Epigenetic modulation of adult hippocampal neurogenesis by extremely low-frequency electromagnetic fields
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Effects of exposure to a 50 Hz sinusoidal magnetic field during the early adolescent period on spatial memory in mice
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(2013):
Toxic effects of 50 Hz electromagnetic field on memory consolidation in male and female mice
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Deficits in water maze performance and oxidative stress in the hippocampus and striatum induced by extremely low frequency magnetic field exposure
Janac B et al.
(2012):
Temporal patterns of extremely low frequency magnetic field-induced motor behavior changes in Mongolian gerbils of different age
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(2011):
Exposure to extremely low frequency magnetic fields induces fos-related antigen-immunoreactivity via activation of dopaminergic D1 receptor
He LH et al.
(2011):
Effects of extremely low frequency magnetic field on anxiety level and spatial memory of adult rats
Lei Y et al.
(2005):
Effects of extremely low-frequency electromagnetic fields on morphine-induced conditioned place preferences in rats
Crasson M et al.
(1999):
50 Hz magnetic field exposure influence on human performance and psychophysiological parameters: two double-blind experimental studies
Lai H et al.
(1998):
Acute exposure to a 60 Hz magnetic field affects rats' water-maze performance
Sienkiewicz ZJ et al.
(1996):
Acute exposure to power-frequency magnetic fields has no effect on the acquisition of a spatial learning task by adult male mice
Sienkiewicz ZJ et al.
(1996):
Prenatal exposure to a 50 Hz magnetic field has no effect on spatial learning in adult mice
Kavaliers M et al.
(1996):
Spatial learning in deer mice: sex differences and the effects of endogenous opioids and 60 Hz magnetic fields
Kavaliers M et al.
(1993):
Brief exposure to 60 Hz magnetic fields improves sexually dimorphic spatial learning performance in the meadow vole, Microtus pennsylvanicus
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