研究のタイプ: 医学/生物学の研究 (experimental study, observational study)

[無線周波電磁放射への職業的ばく露を受けた被験者における細胞毒性学的調査] med./bio.

Cytogenetic investigation of subjects professionally exposed to radiofrequency radiation

掲載誌: Mutagenesis 2006; 21 (2): 139-142

この研究は、無線周波電磁放射(RFR)による遺伝的影響の可能性を調べる試みとして、携帯電話電磁界への職業的ばく露がある被験者の末梢血リンパ球における細胞遺伝学的影響を調査した。これらの被験者のRFRばく露は、「通常」ではあるが、かなり高く、「一般公衆」のばく露よりも明らかに高いため、研究目的に適していると著者らは考えた。結果として、アルカリコメットアッセイ姉妹染色分体交換SCE)、および染色体異常試験において、RFR誘発の遺伝的影響の証拠は示されなかった;また、RFRと化学物質の考えられる複合効果を調べるために、既知の化学的変異原マイトマイシンCを血液細胞に添加した実験では、コメットアッセイまたはSCE試験のテストのいずれにおいても、電磁界ばく露突然変異原の間に共同的な作用は見られなかった、と報告している。

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研究目的(著者による)

To study cytogenetic effects in peripheral blood lymphocytes from 49 subjects who were professionally exposed to mobile phone electromagnetic fields (radio field engineers and other subjects working for two of the Belgian mobile phone operators).

詳細情報

Subjects' blood cells were also exposed to mutagen mitomycin C in order to investigate possible combined effects of radiofrequency irradiation and the chemical.
The data were compared to those obtained in 25 unexposed control subjects.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 450–900 MHz
ばく露時間: repeated daily exposure, at least 1 h/day for 2.3 years (on average)
-
ばく露2: 147.25 MHz–40 GHz
ばく露時間: repeated daily exposure during work
-

General information

Test persons worked for two companies: company 1: 27 radio field engineers company 2: 11 radio field engineers, 11 administrative workers.

ばく露1

主たる特性
周波数 450–900 MHz
タイプ
  • electromagnetic field
ばく露時間 repeated daily exposure, at least 1 h/day for 2.3 years (on average)
Additional information 450 and 900 MHz and other frequencies in the MHz or GHz range
ばく露装置
ばく露の発生源/構造
  • 基地トランシーバ局
  • transmission antennas
Distance between exposed object and exposure source 1 m
Additional information The radio field engineers worked in the maintenance and repair of transmission antennas that were normally switched off for this purpose.
パラメータ

No parameters are specified for this exposure.

ばく露2

主たる特性
周波数 147.25 MHz–40 GHz
タイプ
  • electromagnetic field
ばく露時間 repeated daily exposure during work
ばく露装置
ばく露の発生源/構造
Additional information The administrative staff worked in buildings that were surrounded by RF-dipole antennas operating at 147.25, 164.35, and 169.625 MHz and parabolic antennas with frequencies between 6 and 40 GHz.
パラメータ

No parameters are specified for this exposure.

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

The comet assay, sister chromatid exchange and chromosome aberration tests revealed no evidence of radiofrequency-induced genetic effects.
No cooperative action was found between the electromagnetic field exposure of blood cells and the mutagen using either the comet assay or sister chromatid exchange test.

研究の種別:

研究助成

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